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KMID : 0903520000430020136
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Journal of the Korean Society of Agricultural Chemistry and Biotechnology
2000 Volume.43 No. 2 p.136 ~ p.140
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Steroidal Saponins from the Rhizomes of Asparagus oligoclonos and their Antibacterial Activity
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오세량/Oh, Sei Ryang
박승용/곽용호/성재덕/김금숙/Park, Seung Yong/Kwack, Yong Ho/Seong, Jae Duck/Kim, Geum Soog
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Abstract
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Two steroidal saponins were isolated from MeOH extract of the rhizomes of Asparagus oligoclonos. Using the spectroscopic techniques of ¹H, ^(13)C NMR and 2D NMR, they were identified as 3-O-[β-D-glucopyranosyl-(1→2)-β-D-glucopyranosyl]-(25S) -spirostan-3β-ol and 3-O-[β-D-glucopyranosyl-(1→2)-[β-D-xylopyranosyl-(1→4)]-β-D-glucopyranosyl]-(25S)-spirostan-3β-ol, respectively. They were first isolated from A. oligoclonos. The in vitro antibacterial activities as well as antibacterial spectrums against 20 bacteria strains were investigated with MIC test. Both saponins inhibited the growth of 10 bacteria strains at the concentration of 100㎍/㎖.
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